Database Authors
Maria Doyle1, James I Macrae1, Eleanor C Saunders1, Malcolm J Mcconville1, Ron Caspi2
1Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 2SRI International
Summary LeishCyc is the Pathway/Genome Database (PGDB) for Leishmania major based on the BioCyc ontology. The initial build was based on the genomic data of Leishmania major strain Friedlin v5.2 obtained from the Leishmania major Friedlin project by the Sanger Institute. More information about the LeishCyc project can be found in [Doyle09].

The PGDB, which integrates the biochemical reaction network and metabolic pathways of the organism with its genome, was improved by limited manual curation.

Genome
RepliconTotal GenesProtein GenesRNA GenesPseudogenesSize (bp)NCBI Link
Chromosome 367427281312,682,183
Chromosome 35534532022,090,491
Chromosome 344904801001,866,754
Chromosome 33370364421,583,673
Chromosome 32415413021,565,925
Chromosome 31334328511,484,336
Chromosome 30399395131,403,454
Chromosome 29297295201,212,674
Chromosome 28313311021,160,128
Chromosome 273192635241,130,447
Chromosome 26273272011,091,579
Chromosome 2525525401912,849
Chromosome 2424023460840,950
Chromosome 2123122560772,974
Chromosome 23208197110772,567
Chromosome 2017717601742,551
Chromosome 1817117100739,751
Chromosome 2216816701716,608
Chromosome 1617517212714,659
Chromosome 1917717700702,212
Chromosome 1716115830684,831
Chromosome 1214014000675,347
Chromosome 1317017000654,604
Chromosome 1516816431629,514
Chromosome 1415415004622,648
Chromosome 712812611596,348
Chromosome 11147136101582,575
Chromosome 813313201574,972
Chromosome 9180167121573,441
Chromosome 1014614033570,864
Chromosome 613513401516,874
Chromosome 412612501472,856
Chromosome 512712430465,823
Chromosome 3979511384,518
Chromosome 213574601355,714
Chromosome 1858500268,984
Total:8,5208,2742073932,816,678
Ortholog data available?Yes
Database Contents
Genes8,520
Pathways185
Enzymatic Reactions937
Transport Reactions44
Polypeptides8,286
Protein Complexes7
Enzymes982
Transporters204
Compounds971
tRNAs83
Protein Features7,345
Database Version29.0
Taxonomic Lineage cellular organisms
Eukaryota
Discoba
Euglenozoa
Kinetoplastea
Metakinetoplastina
Trypanosomatida
Trypanosomatidae
Leishmaniinae
Leishmania <genus>
Leishmania <subgenus>
Leishmania major species complex
Leishmania major
Leishmania major strain Friedlin
Genetic Code Number 1 -- Standard
NCBI-Taxonomy347515
Copyright © 2006-2012, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne. All Rights Reserved

References

Doyle09: Doyle MA, MacRae JI, De Souza DP, Saunders EC, McConville MJ, Likic VA (2009). "LeishCyc: a biochemical pathways database for Leishmania major." BMC Syst Biol 3;57. PMID: 19497128

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