Database Authors
Ron Caspi, SRI International
Summary Mycobacterium tuberculosis strain CDC1551, also nicknamed "Oshkosh", is a clinical isolate from a clothing factory worker from the Kentucky/Tennessee, USA, region. It is highly contagious, and infected approximately 80% of the patient's social contacts. However, this strain has not caused epidemics in man and is sensitive to a wide range of drugs. It is also highly virulent in a mouse lung model, producing several orders of magnitude more bacteria than the H37Rv strain when inoculated.

Citations: [Fleischmann02]

Genome
RepliconTotal GenesProtein GenesRNA GenesPseudogenesSize (bp)NCBI Link
Chromosome4,2934,18948564,403,837RefSeq:NC_002755
Ortholog data available?Yes
Database Contents
Genes4,293
Pathways307
Enzymatic Reactions1,935
Transport Reactions69
Polypeptides4,189
Protein Complexes85
Enzymes1,030
Transporters157
Compounds1,396
Transcription Units2,744
tRNAs45
Protein Features4,987
GO Terms30,921
Database Version29.0
Sequence SourceTIGR 2004
Synonyms Mycobacterium tuberculosis CDC1551TIGR 2004
Mycobacterium tuberculosis CDC1551
Taxonomic Lineage cellular organisms
Bacteria <bacteria>
Terrabacteria group
Actinomycetota
Actinomycetes
Mycobacteriales
Mycobacteriaceae
Mycobacterium
Mycobacterium tuberculosis complex
Mycobacterium tuberculosis
Mycobacterium tuberculosis CDC1551
Genetic Code Number 11 -- Bacterial, Archaeal and Plant Plastid (same as Standard, except for alternate initiation codons)
GOLD0071504
NCBI-Taxonomy83331
Relationship to Oxygenaerobe
Trophic Levelheterotroph
Temperature Rangemesophile
Biotic Relationshipparasite
Pathogenicityhuman


References

Fleischmann02: Fleischmann RD, Alland D, Eisen JA, Carpenter L, White O, Peterson J, DeBoy R, Dodson R, Gwinn M, Haft D, Hickey E, Kolonay JF, Nelson WC, Umayam LA, Ermolaeva M, Salzberg SL, Delcher A, Utterback T, Weidman J, Khouri H, Gill J, Mikula A, Bishai W, Jacobs Jr WR, Venter JC, Fraser CM (2002). "Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." J Bacteriol 184(19);5479-90. PMID: 12218036


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